Great McCoy lines

I always found Dr. McCoy’s remarks funny. Here’s why…

after Spock comments that, mentally, V'ger is a child

Commander Leonard 'Bones' McCoy, M.D.: Spock, this "child" is about to wipe out every living thing on Earth. Now, what do you suggest we do? Spank it?
Commander Spock: It knows only that it needs, Commander. But, like so many of us... it does not know what.

Comment: There’s a similar line in Star Trek 4 McCoy says too. (So,This is the probe’s way of saying ‘Hello There’ to the people of Earth.)

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[McCoy trying to discuss what death was like with Spock]
McCoy: C'mon Spock, it's me, McCoy. You really have gone where no man's gone before. Can't you tell me what it felt like?

Comment: Love this one, great stuff. Almost breaks the forth wall.

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Kirk: Out of the way...
Policeman: Sorry, Doctor, I have strict orders...
[Gillian moans in pain]
McCoy: My God man. Do you want an acute case on your hands? This woman has immediate post-parandial, upper-abdominal distention.
[they enter the OR]
Kirk: What did you say she has?
McCoy: Cramps

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General Chang: [prosecuting] Doctor McCoy. What is your current medical status?
McCoy: Well, apart from a bit of arthritis, I'd say pretty good.
Klingons: [actually laugh at the joke, much to McCoy's delight]

Comment: This is actually wrong, only one Klingon laughs in the crowded room, but McCoy is still satisfied with at least getting one Klingon to laugh. One of my favorites

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Kirk and McCoy are beaming down to Regula One]
Spock: Jim, be careful.
McCoy: *We* will.

Comment: Doesn’t Spock care about McCoy too? How rude…